Comparison of Clinical Manifestations and Risk Factors of Death in Two Age Groups Less and More Than 50 Years in Patients with COVID-19

AUTHORS

Ehsan Sharifipour ORCID 1 , Alireza Koohpaei ORCID 2 , Saeed Shams ORCID 3 , Maryam Rahimi ORCID 4 , Mohammad Aghaali ORCID 5 , *

1 Department of Neurology, School of Medicine, Neuroscience Research Center, Qom University of Medical Sciences, Qom, Iran

2 Department of Occupational Health, School of Health, Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran

3 Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran

4 Neuroscience Research Center, Qom University of Medical Sciences, Qom, Iran

5 Department of Epidemiology, School of Medicine, Qom University of Medical Sciences, Qom, Iran

How to Cite: Sharifipour E , Koohpaei A , Shams S, Rahimi M , Aghaali M. Comparison of Clinical Manifestations and Risk Factors of Death in Two Age Groups Less and More Than 50 Years in Patients with COVID-19, Arch Clin Infect Dis.2021 In Press(In Press): e108058. doi: 10.5812/archcid.108058.

ARTICLE INFORMATION

Archives of Clinical Infectious Diseases: In Press (In Press); e108058
Published Online: May 31, 2021
Article Type: Research Article
Received: July 31, 2020
Revised: May 04, 2021
Accepted: May 09, 2021
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Abstract

Background: The COVID-19 pandemic has affected more than 180 countries and has killed more than half a million people, up to now. Risk factors for death are not yet fully identified.

Objectives: the present study aimed at comparing the clinical manifestations and risk factors for death between two groups of patients with COVID-19 aged under and above 50 in Qom Province, Iran.

Methods: The current retrospective cohort study was conducted on 178 patients with COVID-19 in Qom province. Patients were followed up until recovery or death. The source population was divided into four groups, of which 50 patients were randomly enrolled in the study. The first group included patients aged less than 50 discharged after recovery; the second group included patients less than 50 years who died from COVID-19; the third group consisted of patients above 50 discharged after recovery, and the fourth group included patients above 50 who died from COVID-19. The data, including COVID-19 clinical symptoms and presumptive risk factors for death, were collected and compared between groups.

Results: The most common symptoms in hospitalized patients were shortness of breath (82.6%), cough (73.6%), and fever (71.9%), respectively. In the age group of above 50, the prevalence of fever in the recovered subjects was higher than that of the ones who died from the disease (81.8% vs. 53.3%). Headache and loss of senses of smell and taste were also more common in both age groups in the recovered subjects. In the age group under 50, subjects who died had higher BMI values, but in the age group above 50, subjects who died had lower BMIs.

Conclusions: The results of the present study showed that obesity could be a risk factor for death in the age group of under 50. The results also indicated that in both the age groups, extrapulmonary symptoms were more common in recovered patients.

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© 2021, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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