Relationship Between Blood Transfusion and Risk of Nosocomial infection


Maryam Karkhane 1 , * , Zahra Kimiia 1 , Mohammad Reza Akbariyan Torkabad 2 , Seyed Mehdi Mortazavi 2 , Seyed Karim Hossieni Aghdam 2 , Asma Pourhoseingholi 1 , Abdolrazagh Marzban 3 , Mohamad Amin Pourhoseingholi 1 , Mohammad Reza Zali 1

1 Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical sciences, Tehran, IR Iran

2 Baqiyatallah University of Medical Sciences, nursing faculty, Tehran, IR Iran

3 Mashhad University of Medical Sciences, School of Pharmacy, Biotechnology Department, Mashhad, IR Iran

How to Cite: Karkhane M, Kimiia Z, Akbariyan Torkabad M R, Mortazavi S M, Hossieni Aghdam S K, et al. Relationship Between Blood Transfusion and Risk of Nosocomial infection, Arch Clin Infect Dis. Online ahead of Print ; 7(1):21-4.


Archives of Clinical Infectious Diseases: 7 (1); 21-4
Article Type: Research Article


Objective: To investigate association between nosocomial infection, blood products transfusion and microorganisms responsible in patients who hospitalized at ICU (intensive care unit).

Patients and Methods: In this prospective study, 217 patients who were admitted to the ICU of Taleghani Hospital between August 2010 and August 2011 were included. Nosocomial infections were defined using the contacts for disease control and development national nosocomial infections surveillance definitions. Overall, site specific nosocomial infections rates, blood units received, attributable mortality rate and excess length of hospital stay and other variable were considered.

Results: The overall nosocomial infection rate was 24.9% (54 patients). The most common type of nosocomial infection was respiratory tract infections (6.5%, 14) with an attributable mortality rate of 3.7%. In patients who received blood products, 26.6% (37) acquired nosocomial infections. Despite the high percentage of blood transfusion in the hospital, no statistically significant relationship was observed between nosocomial infections and blood product transfusion.

Conclusion: No significance relation was found between NIs and blood transfusion, but was observed between FFP transfusion and NIs. Itsemphasized the need for careful disinfection for FFP transfusion in ears that serve immunosuppressed individual, such as pediatric patients.

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