Orf: Report of Eleven Cases in Five Iranian Families


Mohammad Reza Shirzadi 1 , * , Nahid Pedram 1

1 Department of Zoonosis ,CDC, Iran

How to Cite: Shirzadi M R, Pedram N. Orf: Report of Eleven Cases in Five Iranian Families, Arch Clin Infect Dis. 2007 ; 2(2):e93389.


Archives of Clinical Infectious Diseases: 2 (2); e93389
Published Online: July 30, 2007
Article Type: Brief Report
Received: May 12, 2019
Accepted: July 28, 2007


Background: Parapox virus is the causative agent of Orf disease which is basically seen in sheep and goats. It can betransferred to the human by direct contact with infected animals or indirect contact to infected meat or contaminated butchery instruments like knife. The skin lesions are usually found in fingers.

Patients: Totally, 11 subjects from five families infected with Orf disease were surveyed. The diagnosis was verified on clinical manifestations and pathological changes. Local antiseptic (betadin) and tetracycline ointment were administered for all patients, however, 3 cases were treated with oral antibiotic. No disseminated signs or complications have been reported and patients cured in the third (6 cases) or forth week (5 cases). Little scars were noted in 3 cases after one month follow up.

Conclusion: If there is a similar lesion in the members of a family, one should notice the background of epidemiological and clinical manifestations. Despite the rarity of Orf disease, its spread still exists in urban families, therefore, it is essential to wear gloves at the time of touching meat to prevent infection.



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