Musculoskeletal Problems in Patients with Covid-19: A Review Study


Monireh Motaqi ORCID 1 , Boshra Hatef ORCID 2 , * , Ahmadreza Askari Ashtiani ORCID 3 , Ali Ghanjal ORCID 4

1 Physiotherapy Research Center, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

3 Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

4 Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

How to Cite: Motaqi M, Hatef B, Askari Ashtiani A, Ghanjal A. Musculoskeletal Problems in Patients with Covid-19: A Review Study, Asian J Sports Med.2021 In Press(In Press): e111040.


Asian Journal of Sports Medicine: In Press (In Press); e111040
Published Online: May 25, 2021
Article Type: Review Article
Received: November 21, 2020
Revised: January 24, 2021
Accepted: March 13, 2021
Accepted Article scheduled for 12 (3)


Context: SARS-CoV-2 is a coronavirus, belonging to the beta-coronavirus group, that primarily targets the human respiratory system and causes symptoms similar to those of pneumonia. It should be noted that clinical symptoms of patients with Covid-19 vary in different people. These patients do not only experience respiratory problems. In fact, Covid-19 infection may show a variety of symptoms including fever, shortness of breath, dry cough, nasal congestion, sore throat, nausea, vomiting, myalgia, arthralgia, fatigue (muscular and mental), joint swelling, headache, diarrhea as well as some musculoskeletal symptoms. Therefore, the aim of this article was to investigate the major musculoskeletal problems in patients with Covid-19 through a narrative review study.

Evidence Acquisition: This study collected the related published studies in the pubmed, Science direct, and google scholar source between 2019-2020. The main keywords were COVID-19, coronavirus and musculoskeletal problem such as muscle fatigue, myalgia, arthralgia and joint swelling.

Results: The major musculoskeletal symptoms include muscle fatigue (25.6%), myalgia, and arthralgia (15.5%), joint swelling (as reactive arthritis) and such conditions as joint limitations, tendon shortening and muscle weakness due to prolonged bed rest.

Conclusion: Our findings revealed that attention to musculoskeletal rehabilitation of patients with Covid-19 is as essential as their respiratory rehabilitation. Besides, it would be effective in reducing the physical complications of hospitalization, returning to independence and functional activities and improving the quality of the patients’ life.


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