The Effect of Exercise on Urinary Gamma-Glutamyltransferase and Protein Levels in Elite Female Karate Athletes


Nader Shavandi 1 , Abolfazl Samiei 1 , * , Reza Afshar 2 , Abbas Saremi 1 , Rahman Sheikhhoseini 1

1 Department of Sports Physiology, Arak University, Arak, Iran

2 Department of Nephrology, Shahed University, Tehran, Iran

How to Cite: Shavandi N, Samiei A, Afshar R, Saremi A, Sheikhhoseini R. The Effect of Exercise on Urinary Gamma-Glutamyltransferase and Protein Levels in Elite Female Karate Athletes, Asian J Sports Med. Online ahead of Print ; 3(1):34724. doi: 10.5812/asjsm.34724.


Asian Journal of Sports Medicine: 3 (1); 41-46
Published Online: February 29, 2012
Article Type: Research Article
Received: May 23, 2011
Accepted: September 21, 2011


Purpose: Post exercise proteinuria and increased urinary Gamma-Glutamyl transferase (GGT) levels can be indicative of exercise-induced renal damage. The aim of this investigation is to study the effect of one session of intensive training on renal damage markers and compare their values to those 6 hours after training.

Methods: In this cross-sectional study with pre- and post-test design, 10 elite volunteer female athletes were selected and participated in one training session (2 hours). Urine samples were collected before training, one hour after training, and 6 hours after training. Urinary protein (Pr), creatinine (Cr), and GGT values were measured through laboratory methods and then Pr/Cr and GGT/Cr ratios were computed.

Results: There were significant differences between values of protein, GGT and Creatinine in the three sampling phases (P<0.05). However, no significant differences were observed between values for GGT/Cr and Pr/Cr ratio. There were significant differences between the mean values of Creatinine, protein and GGT within pre-exercise and 1 hour post-exercise and within 1 hour post-exercise and 6 hours post-exercise (P<0.05).

Conclusion: It seems that a session of karate training does not result in renal damage and athletes can continue training after 6 hours.

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