Seroepidemiology of Hepatitis E Virus in Iranian Soldiers


Gholam Ali Ghorbani 1 , * , Seyed Moayed Alavian 2 , Ali Akbar Esfahani 2 , Shervin Assari 2

1 Assistant Professor of Infectious Diseases, Military Health Research Center, Baqiyatallah University of Medical Sciences, Mollasadra Avenue, Vanak Square, [email protected], IR-Iran

2 Military Health Research Center, Baqiyatallah University of Medical Sciences & Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL) & Tehran Hepatitis Center, IR-Iran

How to Cite: Ghorbani G, Alavian S, Esfahani A, Assari S. Seroepidemiology of Hepatitis E Virus in Iranian Soldiers, Hepat Mon. Online ahead of Print ; 7(3):123-126. doi: 10.5812/tjms.10606.


Hepatitis Monthly: 7 (3); 123-126
Article Type: Research Article
Received: June 5, 2007
Accepted: September 20, 2007


Background and Aims: Hepatitis E virus (HEV) is recognized as a common cause of epidemic and sporadic viral hepatitis. HEV outbreaks have been documented in some military forces in the world. The aim of this study was to evaluate anti-HEV antibody in Iranian soldiers.

Methods: In a cross-sectional study, 800 soldiers were selected by simple random sampling in Tehran, Iran in 2006. A questionnaire of demographic data was completed and blood samples were obtained for anti-HEV IgG & IgM antibody. Data were analyzed using student t-test and chi-square using SPSS 12.

Results: All soldiers were male and their mean age was 19 ± 1.2. Education level in 553 (69.1%) of them was high school diploma or higher. Anti-HEV IgG antibody was positive in only 9 (1.1%) of them and IgM was negative in all soldiers.

Conclusions: Approximately 98% of soldiers were at risk for HEV infection and before discovering an effective vaccine, preparation of healthy drinking water and personal hygiene education should be considered for prevention of hepatitis E infection.

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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