Rheumatoid Case with HCV Infection


Bita Behnava 1 , * , Seyed Moayed Alavian 2

1 Tehran Hepatitis Center, [email protected], Tehran, IR.IRAN

2 Associate Professor of Gastroenterology and Hepatology Baqiyatallah University of Medical Sciences, Tehran Hepatitis Center, [email protected], Tehran, IR.IRAN

How to Cite: Behnava B, Alavian S. Rheumatoid Case with HCV Infection, Hepat Mon. Online ahead of Print ; 5(1):7-9.


Hepatitis Monthly: 5 (1); 7-9
Article Type: Discussion


Case Presentation:A 46-year-old woman referred to our center due to abnormality in aminotransferase level during check up. She had a history of blood transfusion 12 years ago. Anti-HCV Ab by ELISA method and HCV RNA by RT-PCR were positive. HCV RNA by Amplicor HCV monitor test counted 800,000 IU/ml and the genotype was 3a by Specific Primer-Targeted Region Core method. Laboratory evaluation revealed: Hb 11.9 mg/dl, WBC 5000 /ml, platelet count 190,000/ ml, ALT 70 IU/ml, AST 65 IU/ml, Alk phosphatase 210, PT 13 second, total protein 7.2 g/dl, albumin 4 g/dl, gama globulin 1.6 g/dl, HBsAg negative and RF positive. She had a history of symmetrical polyarthritis of small joints of upper extremities and morning stiffness for 3 years ago and had been managed as rheumatoid arthritis (RA) since then. She was managed with corticosteroids and methotrexate. Are there any relations between RA disease and HCV infection?

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