Association between serum levels of Adipokines and Polycystic Ovary Syndrome: Review article


Adeleh Razavi 1 , Fatemeh Hashemi 2 , Maryam Emadi 1 , Naghmeh Saadati 1 , Sepideh Haghighi 1 , Mehdi Hedayati 3 , *

1 PhD Student of Biochemistry, Islamic Azad University, Research Branch, Tehran, Iran.

2 PhD Student of Biochemistry, Institute of Biochemistry and Biophysic, Tehran University, Tehran, Iran.

3 Associate Professor Department of Biochemistry Cellular and Molecular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

How to Cite: Razavi A , Hashemi F, Emadi M , Saadati N , Haghighi S , et al. Association between serum levels of Adipokines and Polycystic Ovary Syndrome: Review article, Hormozgan Med J. 2015 ; 19(5):e87639.


Hormozgan Medical Journal: 19 (5); e87639
Published Online: August 12, 2014
Article Type: Review Article
Received: December 19, 2013
Accepted: August 12, 2014


Polycystic ovary syndrome (PCOS) is the most common endocrine disorder associated
with metabolic disorders and infertility. Evidence suggests that the adipose tissue secreted
products, adipokines, play an important role in the pathophysiology of PCOS.
Reciprocally, PCOS influences on the adipokines serum content, also on gene or protein
expression of some of them. Finding out of association between serum levels of
adipokines and PCOS will help to understand the pathology of PCOS and identify
treatment solutions of this syndrome. In this paper, we review the assosiation of several
known adipokines with polycystic ovary syndrome.



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