Acute phase reactants in patients with cerebrovascular accidents in neurology ward, Ali Ebn Abitaleb hospital, Rafsanjan, Iran


Farhad Iranmanesh 1 , * , Zahra Taghipour Shool 2 , Darvish Nejad Shahbadaghi 3

1 Assistant Professor, Department of Internal Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

2 Instructor, Department of Histology, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

3 General Physician.

How to Cite: Iranmanesh F, Taghipour Shool Z, Nejad Shahbadaghi D. Acute phase reactants in patients with cerebrovascular accidents in neurology ward, Ali Ebn Abitaleb hospital, Rafsanjan, Iran, Hormozgan Med J. 2006 ; 9(4):e90559.


Hormozgan Medical Journal: 9 (4); e90559
Published Online: December 31, 2005
Article Type: Research Article
Received: January 19, 2005
Accepted: December 31, 2005


Introduction: Cerebrovascular accident (CVA) is the most important and
prevalent disease of all neurological disorders in adults. It is also one of the most
important causes of morbidity and mortality. The current study was conducted to
evaluate some of the acute phase reactants in patients admitted for ischemic CVA
in neurology ward.
Methods: In this descriptive cross-sectional study, the data were collected
through a questionnaire from the patients admitted in the neurology ward of Aliebn-
abitaleb hospital in Rafsanjan, with primary clinical diagnosis of stroke and
the net diagnosis of ischemic CVA according to their MRI reports, during the
first 24 hours of their admission. Co-morbidities such as infectious diseases,
inflammations and tumors were excluded from the study. The data were analyzed
using EPI6 statistical software.
Results: Some acute phase reactants including platelets (PLT), erythrocyte
sedimentation rate (ESR), C-reactive protein (CRP), and white blood cell (WBC)
were evaluated in 250 patients with ischemic CVA. 60.4% of the cases had a
normal WBC count, while 39.6% showed abnormal WBC. CRP was negative in
all the patients. Also PLT count was in a normal range for all the patients. 67.2%
of the cases showed a normal ESR and 32.8% had abnormal ESR.
Conclusion: In this study, the number of cases with abnormal WBC count and
ESR was more than those reported in most previous researches. It could indicate
the association of some acute phase reactants and thrombotic stroke. Lower ages
of the patients with abnormal WBC in this study, may be due to the higher
prevalence of vasculitic diseases at this range of age, or because of a delay in the
inflammatory reactions at old ages.



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