This investigation aimed at evaluating the effect of iodine supplementation on the IDD impact indicators in a group of 571 hypothyroid iodine deficient schoolchildren. Materials and Methods: Values of levels obtained were compared with data from our previous 1989 study in these villages and results of the comparison showed that total goiter rate decreased by 42% in 1999. Results: A significant decrease in grade 2 goiter concomitant with an increase in grade 1 goiter was seen, P<0.001. Serum T4, T3, TSH concentrations, urinary iodine level and IQ were normal in all children. Mean IQ was higher in children aged 6-10 years as compared to other age groups, P<0.05. Conclusion: Study shows that euthyroidism induced by administration of iodized oil in hypothyroid iodine deficient schoolchildren can be maintained following iodized salt consumption.

"/> This investigation aimed at evaluating the effect of iodine supplementation on the IDD impact indicators in a group of 571 hypothyroid iodine deficient schoolchildren. Materials and Methods: Values of levels obtained were compared with data from our previous 1989 study in these villages and results of the comparison showed that total goiter rate decreased by 42% in 1999. Results: A significant decrease in grade 2 goiter concomitant with an increase in grade 1 goiter was seen, P<0.001. Serum T4, T3, TSH concentrations, urinary iodine level and IQ were normal in all children. Mean IQ was higher in children aged 6-10 years as compared to other age groups, P<0.05. Conclusion: Study shows that euthyroidism induced by administration of iodized oil in hypothyroid iodine deficient schoolchildren can be maintained following iodized salt consumption.

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ARTICLE INFO

Retrospective Analysis of a Long Term Iodine Intervention Program in Rural Iran

AUTHORS

N Salarkia 1 , * , M Hedayati 2 , F Azizi 2

1 National Nutrition and Food Technology Research Institute, [email protected], IR.Iran

2 Endocrine Research Center,Shaheed Beheshti Medical University, IR.Iran

How to Cite: Salarkia N, Hedayati M, Azizi F. Retrospective Analysis of a Long Term Iodine Intervention Program in Rural Iran, Int J Endocrinol Metab. Online ahead of Print ; 5(1):16-25.

ARTICLE INFORMATION

International Journal of Endocrinology and Metabolism: 5 (1); 16-25
Article Type: Original Article
Received: March 14, 2006
Accepted: November 21, 2006
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Abstract

This investigation aimed at evaluating the effect of iodine supplementation on the IDD impact indicators in a group of 571 hypothyroid iodine deficient schoolchildren. Materials and Methods: Values of levels obtained were compared with data from our previous 1989 study in these villages and results of the comparison showed that total goiter rate decreased by 42% in 1999. Results: A significant decrease in grade 2 goiter concomitant with an increase in grade 1 goiter was seen, P<0.001. Serum T4, T3, TSH concentrations, urinary iodine level and IQ were normal in all children. Mean IQ was higher in children aged 6-10 years as compared to other age groups, P<0.05. Conclusion: Study shows that euthyroidism induced by administration of iodized oil in hypothyroid iodine deficient schoolchildren can be maintained following iodized salt consumption.

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