Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics

AUTHORS

M Firoozrai 1 , * , I Nourmohammadi 2 , K Khanaki 2

1 Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, [email protected], I.R.Iran

2 Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, I.R.Iran

How to Cite: Firoozrai M, Nourmohammadi I, Khanaki K. Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics, Int J Endocrinol Metab. Online ahead of Print ; 4(4):202-205.

ARTICLE INFORMATION

International Journal of Endocrinology and Metabolism: 4 (4); 202-205
Article Type: Original Article
Received: January 9, 2005
Accepted: November 26, 2005
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Abstract

The rise and along with this increase there is a growing interest in the efficacy of antioxidant vitamin therapy in the treatment of this malady.

Materials and Methods: In this case-control study, the levels of antioxidant vitamins retinol, -tocopherol and ascorbic acid were measured with HPLC and colorimetric method, in plasma and mononuclear leukocytes of patients with diagnosed Type 2 diabetes(n=62).

Results: We observed significantly lower ascorbicacid levels in mononuclear leukocytes in our study group when compared to controls.

Conclusion: While these results are not definitive, we believe they do indicate that further studies are needed to include a larger segment of the population and an evaluation of dietary intakes and habits.

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