Lupus Anticoagulant Positivity in Diabetes With Retinal Vascular Disease

AUTHORS

s Dash 1 , * , RJ Dash 2 , A Gupta 2

1 Departments of Haematoiogy of Medical Education and Research, [email protected], India

2 Endocrinology of Medical Education and Research, India

How to Cite: Dash S, Dash R, Gupta A. Lupus Anticoagulant Positivity in Diabetes With Retinal Vascular Disease, Int J Endocrinol Metab. Online ahead of Print ; 3(1):33-36.

ARTICLE INFORMATION

International Journal of Endocrinology and Metabolism: 3 (1); 33-36
Article Type: Original Article
Received: January 1, 2004
Accepted: February 1, 2005
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Abstract

To investigate whether lupus anticoagulant (LA) positivity, a frequently associated factor in a variety of thromboembolic events, might be relevant to the pathogenesis of retinal vascular disease in diabetes mellitus.
Materials and Methods:
Eighty-five diabetic patients (44 type 1 and 41 type 2) were examined for total blood counts, screening coagulogram and LA. Results: LA was positive in 20.5% of patients with type 1 diabetes and in 33.3% with patients of type 1 diabetes and retinopathy, whereas, LA was positive in only 7.3% of patients with type 2 diabetes and in 6.4% of them with retinopathy.
Conclusion: These findings suggest that LA positivity might be considered as an additional risk factor in the pathogenesis of microvascular disease in type 1 diabetes.

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