Relationship Between HIV Patients' Mental State and Antiretroviral Medication Adherence


Mohammadreza Heydari ORCID 1 , Morteza Mehraeen ORCID 1 , * , Parisa Keshani ORCID 1 , Marjan Faghih 2

1 Shiraz HIV/AIDS Research Center (SHARC), Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Biostatistics, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Heydari M, Mehraeen M, Keshani P, Faghih M. Relationship Between HIV Patients' Mental State and Antiretroviral Medication Adherence, Int J High Risk Behav Addict. 2021 ; In Press(In Press):e102149.


International Journal of High Risk Behaviors and Addiction: In Press (In Press); e102149
Published Online: May 25, 2021
Article Type: Research Article
Received: February 27, 2020
Revised: September 28, 2020
Accepted: March 01, 2021


Background: Various factors, such as mental disorders, may affect the desire for medication and adherence in HIV/AIDS patients.

Objectives: The present study aimed to determine levels of neurotic disorders and relationships of disorder s level and HAART medication adherence in HIV/ AIDS patients.

Methods: Finally, 150 patients of Behavioral Disease Counseling Center of Shiraz were selected by a convenience method and were evaluated by Symptom Checklist-25 (SCL-25) and Medication Adherence Questionnaire (MAQ).

Results: According to findings, 78% of patients had normal mental health status, and 83% had very good medication adherence. It was also proven that being female, single or divorced, and working in temporary and low-income jobs, reduced mental health status. Higher age and ducation increase patient’s adherence.. Anxiety was the most common and effective disorder. Decreased mental health' status have been shown to reduce drug adherence.

Conclusions: Treatment of mental disorders, especially anxiety can be one of the most effective ways to increase drug compliance in HIV/AIDS patients


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