Pericardial Effusion and Atrial Thrombosis: A Rare Complication of Childhood Leukemia

AUTHORS

Ahmad Jannati 1 , Mohammadreza Farahmandfar 2 , Maral Namdari 2 , Sirous Cheriki 3 , Soheila Zareifar 2 , *

1 Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran

2 Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3 Cardiac Department, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Jannati A, Farahmandfar M, Namdari M, Cheriki S, Zareifar S. Pericardial Effusion and Atrial Thrombosis: A Rare Complication of Childhood Leukemia, Iran J Pediatr. 2016 ; 22(1):117-120.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 22 (1); 117-120
Published Online: March 31, 2012
Article Type: Case Report
Received: September 15, 2010
Accepted: July 19, 2011
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Abstract

Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia.
Case Presentation: We report a 15-year-old girl with T-cell ALL, who presented initially with pericardial effusion and cardiac tamponade and subsequently developed right atrial mass. The mediastinal and right atrial masses were excised by surgical procedure as a treatment strategy for prevention of arrhythmia and sudden death.
Conclusion: T-cell ALL can present with pericardial and mediastinal involvement as an initial manifestation. Pericardiocenthesis and systemic anticancer chemotherapy without local chemotherapy should be considered in these cases.

 

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