Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings

AUTHORS

Hamid Nasri 1 , Mahmoud Rafieian-Kopaei 2 , *

How to Cite: Nasri H , Rafieian-Kopaei M. Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings, Iran J Pediatr. 2014 ; 24(5):565-568.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 24 (5); 565-568
Published Online: September 12, 2014
Article Type: Review Article
Received: December 04, 2013
Accepted: May 02, 2014
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Abstract

Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects.

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  • © 2014, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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