Mortality from Pandemic Influenza A (H1N1) in Iran


MM Gouya 1 , M Nabavi 1 , M Soroush 1 , AA Haghdoust 2 , S Ghalehee 1 , P Hemmati 1 , M Naser Dadras 1 , MK Fallahzadeh 3 , KB Lankarani ORCID 4 , *

1 Center for Disease Control, Ministry of Health and Medical Education, Iran

2 Department of Epidemiology and Biostatistics, School of Health, Kerman University of Medical Sciences, Iran

3 Health Policy Research Center, Shiraz University of Medical Sciences, Iran

4 Health Policy Research Center, Shiraz University of Medical Sciences, [email protected], Iran

How to Cite: Gouya M, Nabavi M, Soroush M, Haghdoust A, Ghalehee S, et al. Mortality from Pandemic Influenza A (H1N1) in Iran, Iran Red Crescent Med J. Online ahead of Print ; 13(10):698-701.


Iranian Red Crescent Medical Journal: 13 (10); 698-701
Article Type: Research Article
Received: April 15, 2011
Accepted: August 10, 2011


Background: Due to worldwide spread of influenza A (H1N1) virus, the World Health Organization declared the first pandemic of influenza in four decades. This study aims to report the mortality from pandemic influenza A (H1N1) in Iran population and its epidemiologic and clinical characteristics up to December 21, 2009.

Methods: The data were obtained from all provinces and reported to center for disease control of Ministry of Health and Medical Education (MOHME) of Iran through nationwide surveillance system for influenza A (H1N1) was implemented by MOHME since April 2009.

Results: Of 3672 confirmed cases of influenza A (H1N1) in Iran between 22 May and 21 December 2009, 140 (3.8%) deaths were reported, mostly in 15-65 year old (yo) age group (67%). The highest admission mortality rate was in > 65 yo group (107 deaths/1000 hospitalized cases). Of decedent patients, 54% had no long term condition or risk factor, 34% had one, 11% had two, and 1% had three. Diabetes mellitus, pregnancy, chronic respiratory diseases and hypertension were the most common underlying conditions. The most common clinical pictures of death were acute respiratory distress syndrome and viral pneumonia. Although 66% of decedent patients received oseltamivir, enough information was not available about time of onset of antiviral therapy.

Conclusion: As death due to influenza A (H1N1) occurs in all age groups and in those with and without any predisposing factors, we recommend health policy makers to provide influenza vaccination for people with underlying conditions and respiratory hygiene for all people.

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