Invasive Pneumococcal Disease (IPD) Serotype Frequency in Iranian Patients


Ali Mehrabi Tavana ORCID 1 , * , Ramazan Ali Ataee 2

1 Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran

2 Department of Medical Microbiology, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, IR Iran

How to Cite: Mehrabi Tavana A, Ataee R A. Invasive Pneumococcal Disease (IPD) Serotype Frequency in Iranian Patients, Iran Red Crescent Med J. Online ahead of Print ; 15(8):740-742. doi: 10.5812/ircmj.4145.


Iranian Red Crescent Medical Journal: 15 (8); 740-742
Published Online: August 4, 2013
Article Type: Research Article
Received: January 10, 2012
Accepted: June 14, 2013


Background: Streptococcus pneumoniae as a Gram positive diplococcic is a major worldwide causative agent of morbidity and mortality among young children and the aged. In addition, Streptococcus pneumoniae is a versatile human pathogen causing infectious disease ranging from mild infection (i.e. otitis media) to life therating pneumonia and meningitidis in many countries

Objectives: The aim of this study was to determine the frequency type of Streptococcus pneumoniae in Invasive pneumococcal disease (IPD) in Iranian patients.

Patients and Methods: A total of 135 Streptococcus pneumoniae strains were isolated from patients infectious suspected of invasive streptococcal disease. They were subjected to PCR and bacteriological methods. Out of which, 134 strains of S. pneumoniae were serotyped and confirmed by PCR method. The data were analyzed by SPSS version 17.0.

Results: The results of this study showed some S. pneumoniae serotypes were found in both sexes and some only in one sex invasive infections. For example, serotypes 10, 14, 18 and 22 were only in female patients with infections.

Conclusions: The analysis of the results had suggested that serotypes 6 from Lung and 19 from Eye are the most abundant bacterial strains isolated from patients. The diseases could be prevented by using the Pneumococcal vaccine.

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF