The Factors Predicting Retroperitoneal Hematoma Following Intra- Aortic Balloon Pump Insertion Site Injury

AUTHORS

Feridoun Sabzi ORCID 1 , Mohammad Rouzbahani 2 , Atefeh Asadmobini ORCID 1 , Reza Heidari Moghaddam 1 , Aghigh Heydari ORCID 1 , *

1 Cardiovascular Research Center, Kermanshah University of Medical Sciences, Kermanshah, IR Iran

2 Cardiovascular Research Center, Kermanshah University of Medical Sciences, Kermanshah, IR Iran *Corresponding

How to Cite: Sabzi F , Rouzbahani M, Asadmobini A, Heidari Moghaddam R , Heydari A . The Factors Predicting Retroperitoneal Hematoma Following Intra- Aortic Balloon Pump Insertion Site Injury, Int Cardio Res J. 2021 ; 15(1):e101955.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 15 (1); e101955
Published Online: March 30, 2021
Article Type: Research Article
Received: February 17, 2020
Accepted: February 08, 2021
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Abstract

Background: Retroperitoneal Hematoma (RPH) is one of the most serious complications
after Intra-Aortic Balloon Pump (IABP) insertion. Although advances in clinical
experience regarding IABP insertion have led to a decrease in vascular complications
such as RPH, its rate has remained considerably high.
Objectives: This study aimed to evaluate the factors predicting RPH following IABP
insertion site injury.
Methods: This retrospective cohort study of 2508 patients undergoing off-pump
Coronary Artery Bypass Graft (CABG) surgery over 4.5 years allowed the identification
and evaluation of all patients with RPH. The patients were divided into with RPH and
without RPH groups. RPH prediction was analyzed by multivariate stepwise logistic
regression analysis. SPSS, version 22 (SPSS Inc., Chicago, IL) was used for statistical
analysis.
Results: RPH developed in 16 patients (overall prevalence: 0.63%), with the highest
frequency in low ejection fraction patients (3%). Female gender, compartment
syndrome, IABP insertion site, preoperative Clopidogrel usage, use of post-operative
inotropic drugs, and body surface area were the predictors of RPH in multivariate
analysis. Moreover, in-hospital mortality was significantly higher in the patients who
had developed RPH compared to those who had not (50% vs. 1.9%, P = 0.004).
Conclusions: RPH is a serious vascular access site complication of IABP, which has been
associated with high morbidity and mortality. The current study findings indicated that
such factors as female gender, BSA, IABP insertion site, preoperative Clopidogrel usage,
IABP usage, and post-operative inotrope drugs use could predict RPH. Identification of
RPH risk factors could in turn prevent this problem.

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