The Effect of HMB Supplementation on Cardiovascular Risk Factors after Four Weeks of Resistance Training in Amateur Athletes


Hamid Arazi 1 , * , Hadi Rohani 2 , Ahmad Ghiasi 1 , Maryam Davaran 3

1 Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran

2 Sport Sciences Research Institute, Tehran, Iran

3 Sciences and Research Branch, Islamic Azad University of Guilan, Rasht, Iran

How to Cite: Arazi H, Rohani H , Ghiasi A , Davaran M . The Effect of HMB Supplementation on Cardiovascular Risk Factors after Four Weeks of Resistance Training in Amateur Athletes, Int Cardio Res J. 2017 ; 9(2):e11400.


International Cardiovascular Research Journal: 9 (2); e11400
Published Online: June 30, 2015
Article Type: Research Article
Received: March 12, 2017
Accepted: December 03, 2014


Background: Nutritional supplements have been widely used in order to enhance athletic performance and improve health.

Objectives: This study aimed to investigate the effect of Beta-Hydroxy Beta-Methylbutyrate (HMB) supplementation on cardiovascular risk factors after 4 weeks of resistance training in athletes.

Patients and Methods: In this double-blind study, 20 male athletes were selected through simple random sampling, were assigned to supplement and control groups, and participated in resistance training 3 sessions a week for 4 weeks. The supplement group consumed 3 g HMB supplement per day and the control group consumed the placebo (rice flour) in this period. Before and after the test period, blood pressure was measured and fasting blood samples were obtained to determine blood lipids and hematological parameters. After all, paired and unpaired t-test were used to examine within and between group differences, respectively. P ≤ 0.05 was considered as statistically significant.

Results: After the training period, no significant differences were found between HMB and placebo groups regarding blood lipids, blood pressure, and hematological parameters.

Conclusions: The results of the present study indicated that HMB supplementation was safe and did not result in any adverse effects. Thus, HMB can be used safely by human as an ergogenic aid for exercise training.


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