Surgical Repair of Post Infarction Ventricular Septal Rupture: An 18 Years' Retrospective Multicenter Study- Where there was no ECMO

AUTHORS

Zohre Mohammadi ORCID 1 , 2 , 3 , Mahmoud Beheshti 2 , 3 , Saman Rostambeigi ORCID 4 , Parham Sadeghipour 4 , Anahita Tavousi 5 , Mahnooosh Foroughi ORCID 6 , *

1 Department of Cardiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

2 Clinical Research and Development Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 a Zohre Mohammadi and Mahmoud Beheshti participated to the same extent in this study.

4 Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran.

5 Department of Cardiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

6 Cardiovascular research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

How to Cite: Mohammadi Z, Beheshti M, Rostambeigi S, Sadeghipour P, Tavousi A, et al. Surgical Repair of Post Infarction Ventricular Septal Rupture: An 18 Years' Retrospective Multicenter Study- Where there was no ECMO. Int Cardio Res J. 2021;15(2):e116606.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 15 (2); e116606
Published Online: June 30, 2021
Article Type: Research Article
Received: May 26, 2021
Accepted: July 19, 2021
READ FULL TEXT

Abstract

Background: Ventricular Septal Rupture (VSR) is a rare but challenging complication
after Myocardial Infarction (MI).
Objectives: The present study aimed to evaluate the surgical outcomes of VSR over 18
years.
Methods: This multicenter study was conducted on 88 patients with post-MI VSR during
2000 - 2018.
Results: A consecutive series of 88 patients with surgical repair of VSR was evaluated. The
patients (n = 11) presenting hemodynamic deterioration at the time of hospital admission
died before any attempt for surgery. The mean intervals between MI and VSR diagnosis
and between admission and operation were 7.5 ± 7.2 and 5 ± 5 days, respectively. VSR
location did not influence the outcomes (P = 0.1). Concomitant coronary bypass was
done for all patients. Only 25 patients survived and left the hospital (13 patients died in
the operating room due to pump weaning failure and 50 patients died in the ICU due to
low cardiac output). The predictors of poor prognosis included low ejection fraction (P
= 0.01), prolonged pump time (P = 0.01), and operation in the second half of the study
period (P = 002). However, the results of multivariate analysis showed that none of them
was an independent predictor of perioperative mortality.
Conclusions: The perioperative mortality rate of VSR has remained high in case of
inaccessibility to assist devices. Hence, VSR repair is recommended to be limited to
certain centers with adequate experiences.

Fulltext

The full-text is available in pdf.

Note: Zohre Mohammadi and Mahmoud Beheshti participated to the same extent in this study.

References

  • 1.

    The references are available in pdf.

  • © 2021, Shiraz University of Medical Sciences.
    COMMENTS

    LEAVE A COMMENT HERE: