The Assessment of Left Ventricular Time-Varying Radius Using Tissue Doppler Imaging


fardin Mirbolouk 1 , Hassan Moladoust 1 , * , Vahid Nikseresht 1 , Bijan Shad 1 , Zahra Ojaghi-Haghighi 2 , Mohammad Assadian Rad 1

1 Guilan University of Medical Sciences, Heshmat Cardiovascular Research Center, Rasht, Guilan, Iran

2 Department of Echocardiography, Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran

How to Cite: Mirbolouk F, Moladoust H, Nikseresht V , Shad B , Ojaghi-Haghighi Z , et al. The Assessment of Left Ventricular Time-Varying Radius Using Tissue Doppler Imaging, Int Cardio Res J. 2017 ; 6(1):e12843.


International Cardiovascular Research Journal: 6 (1); e12843
Published Online: September 30, 2012
Article Type: Research Article
Received: May 17, 2017
Accepted: February 07, 2012


Background: Left ventricular twist/torsion is believed to be a sensitive indicator of systolic and diastolic performance. To obtain circumferential rotation using tissue Doppler imaging, we need to estimate the time-varying radius of the left ventricle throughout the cardiac cycle to convert the tangential velocity into angular velocity.

Objectives: The aim of this study was to investigate accuracy of measured LV radius using tissue Doppler imaging throughout the cardiac cycle compared to two-dimensional (2D) imaging.

Methods: A total of 35 subjects (47±12 years old) underwent transthoracic echocardiographic standard examinations. Left ventricular radius during complete cardiac cycle measured using tissue Doppler and 2D-imaging at basal and apical short axis levels. For this reason, the 2D-images and velocity-time data derived and transferred to a personal computer for off-line analysis. 2D image frames analyzed via a program written in the MATLAB software. Velocity-time data from anteroseptal at basal level (or anterior wall at apical level) and posterior walls transferred to a spreadsheet Excel program for the radius calculations. Linear correlation and Bland-Altman analysis were calculated to assess the relationships and agreements between the tissue Doppler and 2D-measured radii throughout the cardiac cycle.

Results: There was significant correlation between tissue Doppler and 2D-measured radii and the Pearson correlation coefficients were 0.84 to 0.97 (P<0.05). Bland-Altman analysis by constructing the 95% limits of agreement showed that the good agreements existed between the two methods.

Conclusion: It can be concluded from our experience that the tissue Doppler imaging can reasonably estimate radius of the left ventricle throughout the cardiac cycle.




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