Prognostic Value of Troponin T after Elective Percutaneous Coronary Intervention


A Ghaemian 1 , safoora Masoumi 1 , * , RA Mohammadpour 2

1 Mazandaran Heart Cente, Sari, Iran

2 Department of Biostatistics, Mazandaran University of Medical Sciences, Sari, Iran

How to Cite: Ghaemian A , Masoumi S, Mohammadpour R . Prognostic Value of Troponin T after Elective Percutaneous Coronary Intervention, Int Cardio Res J. 2017 ; 5(1):e14234.


International Cardiovascular Research Journal: 5 (1); e14234
Published Online: June 30, 2011
Article Type: Research Article
Received: May 31, 2017
Accepted: January 13, 2011


Background: Cardiac troponin T (cTnT) is a sensitive and specific marker of myocardial necrosis. Prognostic significance of isolated minor elevations of cTnT is a matter of debate .The aim of this study was to assess the impact of minor elevations of cTnT on major adverse cardiac events (MACE) following percutaneous coronary intervention (PCI).

Methods: We measured cTnT levels before and after PCI and evaluated the outcomes of 112 patients with normal baseline cTnT and complex coronary artery disease who required nonemergency PCI.

Results: Elevations (more than 0.03ng/ml) in cTnT were seen in 39 patients (34.8%).The angiographic characteristics of patients with increased cTnT levels had borderline differences compared to those with normal post PCI cTnT levels. Over a mean follow-up duration of 22 months, myocardial infarction (p<0.01) and the combined rate of death, myocardial infarction and revascularization (p<0.001) were significantly higher in patients with increased levels of post PCI cTnT. Estimated 22-month MACE-free survival for patients with increased and normal cTnT levels were 66.7% and 93.2%, respectively.

Conclusion: Isolated minor elevations in cTnT after elective PCI in complex coronary lesions affect long-term prognosis regarding death, myocardial infarction and the need for repeated revascularization procedures.




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