Effects of Six-Week Endurance Training in Liver Enzymes, Lipid Profile, Interleukin 6(IL-6) and High Sensitivity C-Reactive Protein (hs-CRP) Responses in People with a Family History of Coronary Artery Disease

AUTHORS

Farzad Shiri 1 , Amirabbas Monazzami ORCID 1 , * , Mohammad Azizi ORCID 1

1 Department of Sport Physiology, Faculty of Sport Sciences, Razi University, Kermanshah, Iran

How to Cite: Shiri F, Monazzami A, Azizi M. Effects of Six-Week Endurance Training in Liver Enzymes, Lipid Profile, Interleukin 6(IL-6) and High Sensitivity C-Reactive Protein (hs-CRP) Responses in People with a Family History of Coronary Artery Disease, J Arch Mil Med.2021 In Press(In Press): e112886.

ARTICLE INFORMATION

Journal of Archives in Military Medicine: In Press (In Press); e112886
Published Online: May 26, 2021
Article Type: Research Article
Received: January 16, 2021
Accepted: May 02, 2021
Accepted Article scheduled for 9 (2)
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Abstract

Background: Research on the effects of moderate intensity endurance training on inflammatory indices and cardiovascular risk factors is limited.

Objectives: The aim of this study was to determine the effects of six weeks of endurance training on liver enzyme, body composition, fat profile, interleukin 6 and C-reactive protein responses in people with a family history of coronary artery disease.

Methods: Thirty men (30-45years) participated in this study and divided into two groups including control group (n = 10), training group (n = 20), systematically.  The training group program consisted of running on a treadmill for 30 minutes with an intensity of 55 to 60% of maximum heart rate. These training programs were continued three times a week for six weeks. The control group did not perform any exercise program. The ELISA technique were used to measure lipid profile, liver enzymes, interlukine-6 and high sensitivity C-reactive protein, respectively.

Results: The results showed that the variables of weight, liver enzymes, fat profile, interleukin 6 and c-reactive protein were significantly different from the pretest (p <0.05). Also, in the comparison between groups, the results showed that except for the variables of fat percentage and BMI in the other variables of the study, a significant difference was observed (p <0.05).

Conclusions: The results of this study suggest that moderate intensity endurance training could be used as a useful way to reduce weight, levels of inflammatory markers, liver enzymes and cardiovascular risk factors in people with a family history of coronary artery disease.

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© 2021, Journal of Archives in Military Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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