Receiver operating characteristic curve's application and interpretation in medical research

AUTHORS

Mojtaba Sepandi 1 , Hamid Heidarian Miri 1 , Abdolreza Rajaeefard 2 , *

1 PhD student of Epidemiology, Department of Epidemiology, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran

2 Professor of Biostatistics, Department of Epidemiology, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Sepandi M, Heidarian Miri H, Rajaeefard A. Receiver operating characteristic curve's application and interpretation in medical research, Jentashapir J Cell Mol Biol. 2010 ; 1(1):e94039.

ARTICLE INFORMATION

Jentashapir Journal of Health Research: 1 (1); e94039
Published Online: March 30, 2010
Article Type: Research Article
Received: May 19, 2019
Accepted: March 30, 2010
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Abstract

Receiver operating characteristic(ROC), a sensitive diagnostic test that Plots ssensitivity in the y-axis and the rate of false positives in the x-axis, is prepared to be a useful method for evaluating the performance of the diagnostic test. The aim of this study was to introduce the ROC analysis in a nonmathematical and non-statistical way. Important concepts that are needed to use and to interpret this type of analysis correctly include quantitative and qualitative diagnostic tests, sensitivity and specificity, area under the curve, and 95 % confidence intervals. Finally, the ROC analysis software has also been discussed in brief.

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  • © 2010, Jentashapir Journal of Cellular and Molecular Biology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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