Effect of Olea Ointment on Episiotomy Wound Healing in Primiparous Women: A Randomized Clinical Trial


Shokoufeh Torkashvand 1 , Fatemeh Jafarzadeh-Kenarsari ORCID 2 , * , Yalda Donyaei-Mobarrez 2 , Bahare Gholami Chaboki 3

1 Department of Midwifery, Alborz Hospital ,Karaj, Iran

2 Social Determinants of Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran

3 School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

How to Cite: Torkashvand S , Jafarzadeh-Kenarsari F , Donyaei-Mobarrez Y, Gholami Chaboki B . Effect of Olea Ointment on Episiotomy Wound Healing in Primiparous Women: A Randomized Clinical Trial, Jundishapur J Nat Pharm Prod.2021 In Press(In Press): e104570. doi: 10.5812/jjnpp.104570.


Jundishapur Journal of Natural Pharmaceutical Products: In Press (In Press); e104570
Published Online: June 05, 2021
Article Type: Research Article
Received: May 05, 2020
Revised: January 27, 2021
Accepted: January 29, 2021
Primary Published scheduled for 16 (3)


Background: Episiotomy is a surgical incision in the perineal region used to increase the vaginal diameter during delivery. Since the perineal region is not well visible by the mothers and given the possibility of infection of episiotomy wound by vaginal and rectal bacteria, there is a risk of infection and delay in the process of wound healing.

Objectives: The present study was conducted to determine the effect of Olea ointment on episiotomy wound healing in primiparous women.

Methods: This randomized controlled clinical trial was carried out on 73 eligible primiparous women attending Al-Zahra educational hospital in Rasht, Iran in 2017-18. Women were randomly allocated to intervention (n=39) and control (n=34) groups. Episiotomy wound healing was assessed using the REEDA scale before intervention, 2 and 24 hours after the first intervention, as well as 5 and 10 days after childbirth. statistical analysis was performed using descriptive and inferential statistics (Mann-Whitney, Fisher exact test, independent T test, Repeated measurment test, Friedman test, and Chi-square ).

Results: Mean baseline REEDA score was 2.72 ± 0.46 in the Olea ointment group and 2.71 ± 0.46 in the control group and it was not statistically significant. However, the mean score of the Olea ointment group was significant lower than that of the control group at four time points of the follow-up assessments: -0.34( 95% CI: -0.56 to -0.12) at 2 hours after Intervention, -0.63(95% CI: -0.89 to -0.37) at 24 hours after Intervention, -0.30 (95% CI: -0.48 to -0.12) on day 5 postpartum, and -0.29 (95% CI: -0.46 to -0.13) on day 10 postpartum.

Conclusions: Based on the findings of the current study, use of Olea ointment was associated with episiotomy wound healing . More clinical trials are needed to support our findings.


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