Immune response to hepatitis B vaccine in health care workers of Kermanshah

AUTHORS

AR Janbakhsh 1 , * , H Hatami 1 , B Sayad 1 , P Aieni 1 , AH Hashemian 1

1 Iran

How to Cite: Janbakhsh A, Hatami H, Sayad B, Aieni P, Hashemian A. Immune response to hepatitis B vaccine in health care workers of Kermanshah, J Kermanshah Univ Med Sci. 2003 ; 7(1):e81203.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 7 (1); e81203
Published Online: June 19, 2003
Article Type: Research Article
Received: March 15, 2003
Accepted: June 15, 2003
READ FULL TEXT

Abstract

Background & Objectives: hepatitis B is a major health problem in Iran. Although seroconversion in vaccinated persons is estimated to be more than 90%, immune response to hepatitis B vaccine have been reported to be varied in different studies. This study was done to assess the vaccine effects in health care workers (HCWs).

Materials and Methods: I this descriptive, cross sectional study, HBSAb titer in 138 HBCAb negative, vaccinated HCWs in 10 health care centers was assessed using ELISA method. Of 138 HCWs, 60.1% were females and 39.9 males.

Results: 69.9% developed protective immune response. Age was a significant factor in responsiveness. Sex, weight, and last vaccination time had no significant role.

Discussion: In our study, rate of immune response to hepatitis B was low. Thus, revaccination may be necessary for nonresponders. We suggest that cost-effectiveness of the Heberbiovac HB vaccine should be re-evaluated in high risk groups.

Fulltext

The full text of this article is available on PDF

© 2003, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
COMMENTS

LEAVE A COMMENT HERE: