A Low Cost Model To Facilitate Students’ Understanding Of Electron Transfer Chain In Toxicology Lab

AUTHORS

J Pourahmad 1 , *

1 Assistant Professor, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Shaheed Beheshti University of Medical Sciences.

How to Cite: Pourahmad J. A Low Cost Model To Facilitate Students’ Understanding Of Electron Transfer Chain In Toxicology Lab, J Med Edu. 2005 ; 6(2):e105160. doi: 10.22037/jme.v6i2.768.

ARTICLE INFORMATION

Journal of Medical Education: 6 (2); e105160
Published Online: February 28, 2009
Article Type: Research Article
Received: February 28, 2009
Accepted: February 28, 2009
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Abstract

Mitochondrial respiration is a complex process which its biochemistry is often poorly understood by undergraduate students when explained in toxicology lectures. The use of experiments to reinforce their knowledge is important, but not always possible because of low teaching budgets. Therefore, a low cost model, made using water, oil, styrofoam and modeling clay, is presented here to simulate the transduction membrane, and the complexes embedded in it. Using this model, students can represent and understand electron flow and proton translocation, the chemiosmotic hypothesis and the effects of inhibitors and uncouplers. Students that have used this model enjoyed studying mitochondrial respiration and learned and understood the biochemistry of transduction membranes as well as lipid and protein interactions, and were well motivated to study the phenomenon in depth by themselves.

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  • © 2005, Journal of Medical Education. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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