Sleep Quality and Fatigue in Women with Overactive Bladder: A Case Control Study


Nasim Shokouhi 1 , Nafiseh Saedi 1 , Mona Mohseni 1 , Elham Feizabad 1 , Sara Saeedi 1 , Elaheh Miri Ashtiani 2 , *

1 Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran

2 Emam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

How to Cite: Shokouhi N, Saedi N, Mohseni M, Feizabad E, Saeedi S, et al. Sleep Quality and Fatigue in Women with Overactive Bladder: A Case Control Study, Shiraz E-Med J.2021 In Press(In Press): e112902.


Shiraz E-Medical Journal: In Press (In Press); e112902
Published Online: May 25, 2021
Article Type: Research Article
Received: January 21, 2021
Revised: February 23, 2021
Accepted: March 02, 2021


Background: Overactive bladder (OAB) syndrome, a condition with urgency, is often characterized by increased daytime frequency and nocturia. OAB is a highly prevalent condition that drastically impacts the quality of patients’ life.  

Objectives: This study was conducted to investigate sleep disturbance and fatigue in women with overactive bladder (OAB) by reliance on two validated questionnaires.

Methods: This case-control study was performed on 70 patients recognized with OAB and 70 women in control group. We employed validated questionnaires, namely PSQI and FSS to comparatively assess sleep disturbance and fatigue symptoms.

Results: The participants’ mean age was 44.50±12.64 year-old. The mean PSQI score was 13.24±3.67 (range: 6 to 22) and the mean FSS score was 39.05±15.12 (range: 9 to 63). Furthermore, the mean PSQI score (P value<0.001) and the FSS score average (P value<0.001) were significantly higher in OAB women rather than control group. In women with OAB, there was a significantly positive correlation (p value= 0.007) between PSQI and FSS score. Furthermore, this correlation was observed between urgency urinary incontinence at night, and PSQI (p value= 0.047) and sleep disturbance (p value= 0.023) as well as between nocturia and sleep efficiency (p value= 0.012), sleep disturbance (p value= 0.001), sleep latency (p value=0.007) and FSS score (p value= 0.032). In addition, a significantly direct correlation (p value=0.022) between urgency urinary incontinence during the day and daytime dysfunction item was found.

Conclusions: The study illuminated that sleep disorder is common in patients with OAB and it seems urinary problem assessment is a prerequisite for any sleep medication prescription.


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