Seroprevalence and Co-Infection of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus in Nigeria.


JD Mawak * , +

How to Cite: Mawak J. Seroprevalence and Co-Infection of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus in Nigeria., Shiraz E-Med J. Online ahead of Print ; 13(1):20506.


Shiraz E-Medical Journal: 13 (1); 33-39
Published Online: January 1, 2012
Article Type: Research Article
Received: December 22, 2008
Accepted: March 1, 2009


Background: Herpes simplex virus type 2 (HSV-2) is a sexually transmitted virus that is the most common cause of genital ulceration worldwide. The increasing evidence that HSV-2 infection could significantly enhance the rates of sexual transmission and acquisition of hu-man immunodeficiency virus (HIV) in developing countries informed our design of this study.

Objective: To determine the seroprevalence and co-infection of HSV-2 and HIV and to evaluate their association with demographic factors among adults (?15yrs) in Pankshin.

Methods: One hundred and eighty blood samples were collected from adults, age ?15 years from Town Clinic Pankshin and General hospital Billang Shippang in Pankshin Local Govern-ment Area of Plateau State. DetermineTM and Stat pak rapid test kits were used to screen the collected samples for antibodies to HIV. The seroprevalence of HSV-2 was determined using Diapro HSV-2 type specific ELISA Kit according to the manufacturers instructional manual.

Results: The estimated prevalence of HSV-2 was 24.4% and it was higher among women (26.09%) than among men (21.53%). That of HIV was 19.49%; men had a prevalence rate of 4.69% while that of women was 5.22%.

Conclusion: HSV-2 antibodies were frequent in the study group, genital herpes was not re-ported by the HSV-2 positive subjects, indicating low awareness of the HSV-2 infection. The prevalence of HIV however was not that significant. The percentage of co-infection was 2.8%.

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