Side Effects of Gadolinium Enhanced Magnetic Resonance Imaging in Patients with Renal Failure, a Review

AUTHORS

E Ghanei 1 , * , M Homayouni 2

1 Assistant Professor, Urology and Nephrology Research Center (UNRC) and Section of Nephrology, Department of Internal Medicine

2 Associate Professor, Department of Internal Medicine, Shohada Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran

How to Cite: Ghanei E, Homayouni M. Side Effects of Gadolinium Enhanced Magnetic Resonance Imaging in Patients with Renal Failure, a Review, Shiraz E-Med J. Online ahead of Print ; 12(2):20474.

ARTICLE INFORMATION

Shiraz E-Medical Journal: 12 (2); 77-86
Published Online: April 2, 2011
Article Type: Review Article
Received: January 3, 2011
Accepted: March 5, 2011
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Abstract

Iodinated contrast media in patients with chronic kidney disease induce to loss of residual renal function. So Magnetic resonance imaging with gadolinium has replaced iodinated contrast agents in these patients. Nephrogenic systemic fibrosis is a recently identified disorder seen only in patients with kidney failure, particularly in patients on dialysis. The evidence has implicated gadolinium as the 2 main cause of this disorder Skin involvement occurs in all patients and some have systemic manifestations. It is under-diagnosed by clinicians who are unfamiliar with the condition. Although no Therapy has shown consistent benefit, but prevention in high risk patients should be considered.

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© 2011, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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