Probability of Continuation: With Triphasic and Monophasic (LD).


Z [email protected] 1 , * , L Manzouri 2 , P Golmohammadi 3

1 Associate Professor, Department of Community Medicine, Isfahan University of Medical Sciences, Isfahan, Iran,

2 Specialist, Community Medicine, Isfahan University of Medical Sciences, Isfahan, Iran,

3 General practitioner, Department of Medicine, Isfahan Univer-sity of Medical Sciences, Isfahan, Iran.

How to Cite: [email protected] Z, Manzouri L, Golmohammadi P. Probability of Continuation: With Triphasic and Monophasic (LD)., Shiraz E-Med J. 2009 ; 10(2):e93755.


Shiraz E-Medical Journal: 10 (2); e93755
Published Online: April 01, 2009
Article Type: Research Article
Received: May 15, 2019
Accepted: December 10, 2008


Introduction:: Despite the same complications for LD and triphasic pills, it seems as if the continuation times for the two birth control methods are different.

Aims:: To compare the continuation times and side effects of triphasic and monophasic LD use, and identify factors related to continuation and discontinuation.

Methods and Materials:: A historical cohort study was conducted in Isfahan, Iran to deter-mine and compare the probability of 5 years continuation of low dose monophasic (223) and triphasic (163) use among 386 reproductive married women.
Statistical analysis used: The continuation time of triphasic pill and LD pills were compared with Kaplan Meier by SPSS11.5 software.

Results:: The cumulative proportion of continuation was significantly different between triphasic and LD groups in the first year of use [0.98 (LD) VS 0.84 (tri phsic)]. It was found that age, number of living children, education level and employment status didn’t have any role in choosing contraceptive method (p>0.05). In each group there was a significant rela-tionship between these variables and median duration of OCP use. Despite similar complica-tions and total discontinuation, 5 year continuation time of triphasic was lower than that observed for LD.

Conclusions:: It seems as though consumption of triphasic OCP requires more attention, as it should be taken on a regular schedule, and missing a dose for more than two hours reduces its efficacy. Therefore, health care professions should consider more factors before offering clients triphasic pills in order to reduce discontinuation time.


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