Tear Film Break-Up Time: Comparison between Patients using Psychiatric Drugs and Healthy Individuals


Mohammad Mojtaba Keikhayfarzaneh 1 , Mohammad Aghazade-Amiri 2 , Mohsen Akhgary 2 , Parvin Dibajnia 3 , *

1 oung Researchers Club, Zahedan Branch, Islamic Azad UniversityI, Zahedan, Iran

2 Department of Optometry, Shahid Behesh ti University of Medical Sc iences, Faculty of Rehabilita tion Sciences, Tehran, Iran

3 Department of Psychiatry, Faculty of Re habilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

How to Cite: Keikhayfarzaneh M M, Aghazade-Amiri M, Akhgary M, Dibajnia P . Tear Film Break-Up Time: Comparison between Patients using Psychiatric Drugs and Healthy Individuals, Zahedan J Res Med Sci. 2014 ; 16(9):-.


Zahedan Journal of Research in Medical Sciences: 16 (9)
Published Online: May 26, 2013
Article Type: Short Communication
Received: April 10, 2013
Accepted: May 01, 2013


Background: Ocular dryness is a well-recognized adverse side effect of many medications. The purpose of this study was to compare tear film stability between psychiatric patients that use lithium carbonate or carbamazepine and normal cases.

Materials and Methods: Tear film break up time test was performed in three groups, 30 patients using lithium carbonate, 30 patients using carbamazepine and 30 normal cases. Values of the TBUTs were compared among groups by the independent t-test.

Results: Differences between both of patients and control groups were significant (p<0.0001).

Conclusions: The results show that these drugs contribute to decrease of tear film break up time.


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