The Application of Theta Burst Stimulation in Negative Symptoms of Patients with Schizophrenia

AUTHORS

Reza Kazemi 1 , * , Reza Rostami 1 , Marco Antonio Marcolin 2 , Sanaz Khomami 3 , Mohammad-Reza Khodaei 4

1 Department of Psychology, Faculty of Psychology and Educational Sciences, University of Tehran, Tehran, Iran

2 Department of Psychiatry, Institute of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil

3 Department of Psychology, Faculty of Psychology and Educational Sciences, University of Shahid Chamran, Ahvaz, Iran

4 Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran

How to Cite: Kazemi R, Rostami R, Antonio Marcolin M, Khomami S, Khodaei M. The Application of Theta Burst Stimulation in Negative Symptoms of Patients with Schizophrenia, Zahedan J Res Med Sci. 2012 ; 14(10):e93202.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 14 (10); e93202
Published Online: October 24, 2012
Article Type: Short Communication
Received: January 11, 2012
Accepted: February 14, 2012
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Abstract

Background : The aim of this research is study of theta burst stimulation on left dorsolateral prefrontal cortex in remission of negative symptoms in patients with schizophrenia.
Materials and Methods : In a placebo, double blind and randomized study, 10 patients with schizophrenia assigned in experimental and control group. The experimental group received 20 sessions of TBS with 50 Hz frequency, but control group were treated just with sham coil. All the patients were appraised before, the 10th sessions and after the treatment. The treatment efficacy was calculated with ANOVA.
Results : The results indicated that the experimental group had statistical difference to control group in negative symptoms (p>0.007) and social functioning (p>0.01). But there weren’t any significant difference in quality of life and depression between two groups.
Conclusion : Theta burst stimulation can be mentioned as an efficacious treatment for people with schizophrenia.

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  • © 2012, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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