Comparing of Cu/Zn SOD Gene Expression of Lymphocyte Cell and Malondialdehyde Level in Active Men and Women after Physical Training

AUTHORS

Bakhtiar Tartibian 1 , * , Behrouz Baghaiee 1 , Behzad Baradaran 2 , Mohammadreza Aliparasty 3 , Shohreh Almasy 3

1 Department of Exercise Physiology, School of Physical Education, Department of exercise physiology, Urmia University, Urmia, Iran

2 Department of Immunology, Tabriz University of Medical Sciences, Immunology research center, Tabriz, Iran

3 Department of Immunology, Tabriz University of Medical Sciences, Department of immunology, Tabriz, Iran

How to Cite: Tartibian B, Baghaiee B , Baradaran B , Aliparasty M , Almasy S . Comparing of Cu/Zn SOD Gene Expression of Lymphocyte Cell and Malondialdehyde Level in Active Men and Women after Physical Training, Zahedan J Res Med Sci. 2012 ; 14(7):e93311.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 14 (7); e93311
Published Online: November 10, 2011
Article Type: Research Article
Received: August 06, 2011
Accepted: September 03, 2011
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Abstract

Background: The purpose of this study is to compare Cu/Zn SOD mRNA and MDA level as a result of a session incremental exercise in active women and men. 
Materials and Methods : This research is a quasi-experimental study with repeated measurements in which 14 active female and 13 male subjects with age range 22-24 participated voluntarily. Then, blood was taken from brachial vein of the subjects in three stages before and after GXT (Graded exercise test) and 3 hours after that and SYBER Green PCR Master mix reagent Kit and Real time-PCR were used to measure Cu/Zn SOD mRNA and spectrophotometer was used to measure MDA level.
Results: MDA levels increased significantly in men during the recovery stage and after the exercise (p1=0.012 and p2 =0.014), but it did not increase significantly in active women. Also, MDA difference between the two genders was not reported significant in any of the exercise stages. Cu/Zn SOD gene expression did not increase significantly in either sex.
Conclusion: The risk of injury from free radicals is more probable in active men than active women and vigorous physical activity does not significantly increase the Cu/Zn SOD gene expression. 

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  • © 2012, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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