The Relationship between Clinical and Chemical Hyperandrogenism in 14-18-Years- Old Girls

AUTHORS

marzieh akbarzadeh 1 , * , Tahereh Naderi 2 , Mohammad Hossain Dabbaghmanesh 3 , Hamidreza Tabatabaee 4 , Zahra Zareh 5

1 Faculty of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Midwifery, Marvdasht Health Center, Shiraz University of Medical Sciences, Marvdasht, Iran

3 Department of Endocrinology, Shiraz Endocrine and Metabolism Research Center, Shiraz, Iran

4 Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran

5 Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: akbarzadeh M, Naderi T, Dabbaghmanesh M H, Tabatabaee H, Zareh Z. The Relationship between Clinical and Chemical Hyperandrogenism in 14-18-Years- Old Girls, Zahedan J Res Med Sci. 2012 ; 14(4):e93469.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 14 (4); e93469
Published Online: July 27, 2011
Article Type: Research Article
Received: May 10, 2011
Accepted: May 25, 2011
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Abstract

Background: One of the most common endocrine disorders in women's medicine is the increased androgen and the symptoms of increased androgens in women such as polycystic ovary syndrome. The two main components to diagnose this syndrome are menstrual disorder and clinical or laboratory hyperandrogenism, but other causes should be ruled out in order to confirm the diagnosis. This study aims to examine clinical Hyperandrogenism in female students of 14 to 18 years old in Shiraz in 2010.
Materials and Methods: This cross-sectional study was conducted on 3200 female high school students of 14-18 years old in Shiraz. Data collection tools include questionnaires containing personal details, clinical Hyperandrogenism features (acne, alopecia and hirsutism based on Freeman-Galway scale) and test results. The ultrasound was conducted based on Adams criteria. The data results are analyzed using SPSS-15 software and χ2 and t statistical tests.
Results:  In this study, the frequency of hirsutism is 3.2%, prevalence of acne is 5% and alopecia is 4.2%. Mean of free testosterone (1.647±0.835) was higher in the group with hirsutism, acne and alopecia. Independent t-test showed no significant relationship between patients with hirsutism, acne and alopecia and non-affected people in terms of mean of total testosterone and free testosterone. However, there is a significant relationship between people with acne and hirsutism and polycystic ovary compared with those with acne and hirsutism and those without polycystic ovary (p >0.05).
Conclusion: This study indicated that clinical and chemical hyperandrogenism can be a criterion to diagnose with polycystic ovary syndrome, but ultrasound was not helpful.

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  • © 2012, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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