Effects of Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Inflammation and Liver Functional Tests among Type 2 Diabetic Patients

AUTHORS

Leila Azadbakht 1 , * , Azam Borzoi 2 , Ahmad Esmaillzadeh 1

1 Associate Professor of Nutrition, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

2 BSc of Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

How to Cite: Azadbakht L, Borzoi A, Esmaillzadeh A. Effects of Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Inflammation and Liver Functional Tests among Type 2 Diabetic Patients, Zahedan J Res Med Sci. 2012 ; 14(2):e93573.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 14 (2); e93573
Published Online: February 08, 2012
Article Type: Research Article
Received: April 26, 2011
Accepted: June 08, 2011
READ FULL TEXT

Abstract

Background : Considering that the new cardiovascular risk factors are important among type 2 diabetes. We evaluated the effects of the Dietary Approaches to Stop Hypertension (DASH) eating pattern on inflammation and novel cardiovascular risk factors in type 2 diabetic patients.

  Materials and Method : In this eight-weeks crossover randomized clinical trail, 31 type 2 diabetic patients were on a control diet or the DASH diet. Fruits, vegetables, whole grains, low-fat dairy products are consumed in high amounts in this diet. However, saturated fat, total fat, cholesterol, refined grains, and sweets are recommended in low amounts. DASH diet had a total of 2,400 mg sodium per day. There was a four week washout between two trial phases. C-reactive protein level, coagulation indices and hepatic function tests were measured at baseline and after each phase of trial.

  Results : The mean percent change for plasma C-reactive protein level was -26.9±3.5% after the DASH diet and

  -5.1±3.8% after the control diet (p=0.001). Both alanine aminotransferase and aspartate aminotransferase levels were significantly reduced after consuming the DASH diet compared to the control diet (-14.8±3.0 % vs -6.6±3.4% p=0.001, -29.4±3.7% vs -5.9±1.4% p=0.001, respectively). The DASH diet reduced the plasma fibrinogen level compared to the control diet (-11.4±3.6% and 0.5±3.4% p=0.03, respectively). 

  Conclusion : Among diabetic patients, the DASH diet can play an important role in reducing inflammation, plasma levels of fibrinogen and liver aminotranferases. Future long-term studies are recommended . [ZJRMS, 2012 14(2): 9-15 ]

Fulltext

The full text of this article is available on the PDF file.

 

 

References

  • 1.

    The References of this article are available on the PDF file.

  • © 2012, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
    COMMENTS

    LEAVE A COMMENT HERE: