Seroepidemiologic assessment of Hepatitis E virus in women of reproductive age, Gorgan

AUTHORS

Abdolvahab Moradi 1 , Sima Besharat 2 , * , Mohammad Mehdi Minaiifar 2 , Gholamreza Roshandel 2 , Alijan Tabaraii 3

1 Associated Professor, Dept. of Virology, Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

2 General Practitioner, Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

3 Assistant Professor, Dept. of Virology, Golestan Research Center of Infectious Diseases, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

How to Cite: Moradi A, Besharat S, Minaiifar M M, Roshandel G, Tabaraii A. Seroepidemiologic assessment of Hepatitis E virus in women of reproductive age, Gorgan , Zahedan J Res Med Sci. 2010 ; 12(1):e94352.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 12 (1); e94352
Published Online: January 14, 2010
Article Type: Short Communication
Received: April 18, 2009
Accepted: November 15, 2009
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Abstract

 Background: Hepatitis E virus can be disseminated oral-fecally and its fulminant form mortality rate maybe up to 20% in the third trimester of pregnancy. This study aimed to assess the sero-epidemiology of HEV in women of reproductive age in Gorgan, Iran.

  Materials and m ethods: In this cross-sectional descriptive study, 1200 women ages between 17-45 years were recruited from laboratories and health care systems of Gorgan. Demographic data was recorded in the checklists. ELISA method (DIAPRO) was done to evaluate the anti-HEV antibody. Data were entered into SPSS-13 software for analysis by Chi-squared and Fisher exact test.

  Results: Mean ( ± SD) age of the cases was 27.41 ( ±6.33). Among 1200 subjects, 76(6.3%) cases had positive anti-HEV antibodies. Age and ethnicity had a significant relationship with HEV (p-value<0.05), but no significant relationship was seen between other variables.

  Conclusions: According to our results and due to higher positive cases in 30-40 years-old women, more researches especially in pregnant women are suggested.

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  • © 2010, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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