Effects of electromagnetic field with 25, 50 and 100 Hz frequency on serum alanine transaminase and aspartate transaminase activity in mice

AUTHORS

Majid sirati Sabet 1 , * , p Silakhori 2

1 Dept of Biochemistry and Genetic, Faculty of Medicine, Ghazvin University of Medical Sciences and Health Services Ghazvin, Iran.

2 Falagh Industrial School, Tehran, Iran

How to Cite: sirati Sabet M, Silakhori P. Effects of electromagnetic field with 25, 50 and 100 Hz frequency on serum alanine transaminase and aspartate transaminase activity in mice, Zahedan J Res Med Sci. 2007 ; 9(3):e94803.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 9 (3); e94803
Published Online: July 17, 2007
Article Type: Research Article
Received: April 02, 2007
Accepted: June 30, 2007
READ FULL TEXT

Abstract

Background: The widespread use of electric power results in exposure of humans to low level
50/60 Hz electric and magnetic fields. There are some controversial reports about the impact of
electromagnetic field (EMF) on biological systems. Alanine transaminase (ALT) and aspartate
transaminase (AST) are nonspecific enzymes of plasma whose elevations are an indicator of
cellular damage. The aim of this investigation was to study the effect of low frequency EMF
exposure on activities of serum ALT and AST of mice.
Materials and Methods: In this experimental study twenty four male mice weighting 30 ± 5 g were
divided into four groups each of six animals. The treatment groups were exposed to electromagnetic
field (EMF) tensity of 250 microtesla and with frequency of 25, 50 and 100 Hz for one hour per day
for thirty days. The control group was in the similar situation without exposure to EMF. The blood
samples were taken after thirty days. ALT and AST activities were determined at 37oC by kinetic
method. The data were analyzed by SPSS (version 11.5) computer software.
Results: Mice serum ALT activity was 84.3 ± 6.2 , 89.8 ± 14.3 and 84.8 ± 10.8 IU/L and AST
activity was 183.8 ± 9.1 , 185.5 ± 10.5 and 163.5 ± 15.7 IU/L in groups exposed to 25, 50 and 100
Hz electromagnetic fields respectively. Significant differences were detected in ALT and AST
activities between exposed groups and control group (P< 0.05).
Conclusion: In this study, 250 microTesla intensity EMF with 25, 50 and 100 Hz frequency
increased the mice serum ALT and AST activities. Serum ALT and AST activities enhancement can
be due the electromagnetic fields effect on liver.

Fulltext

The full text of this article is available on the PDF file.

References

  • 1.

    The References of this article are available on the PDF file.

  • © 2007, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
    COMMENTS

    LEAVE A COMMENT HERE: