Evaluation of immune response of Hepatitis B vaccination in Zahedan infants


Masoud Salehi 1 , * , Esmail Sanei-Moghadam 2 , Soheila Khosravi 2

1 Tropical and Infectious diseases dept, faculty of medicine, Zahedan university of medical sciences and health services, Zahedan, Iran.

2 South eastern center of blood transfusion, Zahedan, Iran.

How to Cite: Salehi M, Sanei-Moghadam E, Khosravi S. Evaluation of immune response of Hepatitis B vaccination in Zahedan infants, Zahedan J Res Med Sci. 2002 ; 4(3):e95330.


Zahedan Journal of Research in Medical Sciences: 4 (3); e95330
Published Online: August 28, 2002
Article Type: Research Article
Received: July 01, 2002
Accepted: July 31, 2002


Hepatitis B vaccination is the best way of prevention of Hepatitis B infection and chronic
liver disease as well as hepatocellular carcinoma. Mass vaccination of Hepatitis B in neonate
has started in Iran since 1993. So evaluation of vaccination is essential. In this study,
seroconvertion of antiHBs evaluated after complete vaccination of Hepatitis in 15-23 month old
infants. 324 infants selected randomly from general population of Zahedan. The positivity rate
of antiHBs in male, female and total samples was 77%, 80% and 78.4, respectively. This ratio
was less than expected, so we suggest further study about this subject.


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